A Blog About Psoriatic Arthritis

Posts Tagged ‘rheumatoid arthritis mortality rate’

Rheumatoid Arthritis Mortality Rate

Thursday, July 29th, 2010

The disease fighting properties of Selenium – why you should supplement

Selenium is an essential nutrient that offers antioxidant function, which helps to boost the immune system. Found in soil, plants absorb it and it does not diminish when processed. This trace mineral is essential in the human body as it assists both the immune system and operation of the thyroid gland.

 

These findings do make sense as selenium fights free radicals and therefore it will help those who suffer from arthritis and certain heart conditions. Poor heart function and cardiomegaly (enlarged heart) are often linked to this deficiency; this is because it reduces the stickiness of the blood and at the same time, decreasing clotting. At the same time, good (HDL) cholesterol is increased and bad (LDL) cholesterol lowered.

 

With its immune-boosting properties, selenium assists the body in fighting disease. It fights against herpes, which causes shingles and cold sores and current studies are performed to test its efficiency against HIV and AIDS. The anti-inflammatory properties are thought to be beneficial against conditions that include eczema, lupus, psoriasis and rheumatoid arthritis.

 

In addition to low levels of nutrition provided by fresh produce, gastrointestinal disorders or gastric surgery could hamper the absorption of sufficient nutrients. These disorders, which include Chron’s Disease, are known to inhibit the absorption of selenium.  Excess selenium may, in rare cases cause selenosis. This condition manifests in symptoms such as mild nerve damage, blotchy nails, hair loss and stomach upsets. This is however a rare condition and which is usually diagnosed in people who were involved in industrial accidents.

 

More research is required to prove a link to increased selenium levels and a reduced rate of mortality amongst cancer patients. However, it is believed that the incidence of certain cancer types is reduced because of selenium. These cancers include cancer of the prostate, lunch and colorectal cancer. This research also suggests that cancer risk is affected in two different ways. Apart from the anti-oxidant properties that protect the body from the affects of free radicals, it is also thought to prevent or slow the growth of tumors. This helps to enhance the activity of immune cells and to suppress the circulation of blood to the tumor.

 

Soybeans, wheat and corn are some of the best sources of selenomethionine. This is the analogue form of methionine and it can be used by the body to replace methionine. It serves as storage for selenium in the tissues and organs. It is thought to be the form of selenium, which is best absorbed and utilized. Supplements may contain substances that are not derived from plants or other organic sources. These substances usually include sodium selenate and sodium selenite.

 

This trace mineral affects many other body processes, but its importance was only realized in the late 1970s. Since then, it was found to be helpful in preventing cancer of the liver, pancreas, esophagus, bladder, rectum, cervix and ovaries. It also showed hope in preventing leukemia.

 

Supplementing with selenium may prevent with causes of impaired vision, such as macular degeneration and cataracts. These conditions are common, especially in the elderly.

 

Since the soil in which vegetables are grown determines the amount of trace elements provided by the food sources, it is not easy to meet the required daily intake for optimum health. Therefore, supplementation is often necessary. The RDA (Recommended Dietary Allowance) of Selenium is 55 mcg per day for adults. Deficiencies are common in countries such as Russia and China and the occurrence of Keshan disease is a result. Adequate levels of essential selenium could worsen the effects of an iodine deficiency, which also affects the functioning of the thyroid gland. 

Before adding <a href=”http://www.mineralifeonline.com/pd-selenium-8oz.cfm”>selenium supplements</a> to your daily health program, get all the facts about mineral supplements by visiting <a href=”http://www.mineralifeonline.com”>www.mineralifeonline.com</a> and download your FREE audio, Minerals: what your body needs and why.

About the Author

Neil Butterfield

RAW FOOD WEIGHT LOSS 178 pounds! Dave the Raw Food Trucker VIDEO #10

Rheumatoid Arthritis Mortality

Thursday, May 10th, 2007

Why Rheumatoid Arthritis Should be Treated- Aggressively!

Multiple studies have demonstrated that early aggressive management of rheumatoid arthritis (RA) is beneficial.

What many patients don’t understand is why this is so important. Beyond the pain, stiffness, and inability to perform activities of daily living, moist patients aren’t aware of the other insidious dangers that rheumatoid arthritis- if not optimally managed- poses.

The very substances- called cytokines- that promote the chronic inflammation of joints are also responsible for more serious problems affecting internal organs. Examples of some of these cytokines are TNF-alpha, interleukin-1 (IL-1), and IL-6.

These cytokines lead to insulin resistance, abnormal function of cells that line blood vessels, and abnormalities of cholesterol metabolism, causing increases in total cholesterol, low density lipoproteins (LDL- “bad cholesterol”), and triglycerides. The end result is a marked tendency to atherogenesis- “hardening of the arteries”.

This hardening of the arteries is associated with cardiovascular disease leading to a marked tendency to stroke and heart attack. The insulin resistance also contributes to other metabolic disturbances. These metabolic problems can be aggravated by the natural tendency for patients with poorly controlled RA to be subject to stress, poor dietary habits, and less than sufficient exercise. The bottom line is that the life expectancy of a patient with rheumatoid arthritis is shortened by ten to fifteen years compared with age-matched controls.

One study demonstrated a two-fold higher risk for coronary heart disease in patients with rheumatoid arthritis compared with people who did not have rheumatoid arthritis (Satter N, McInnes IB. Curr Opin Rheumatol. 2005; 17: 286-292).

Another study showed that women with rheumatoid arthritis who had had rheumatoid arthritis for at least ten years were three times more likely to have had a heart attack compared to women without RA (Solomon DH, Karlson EW, Rimm EB, et al. Circulation. 2003; 107: 1303-1307).

So… it is this important but little emphasized complication of the disease that must be emphasized to patients.

Fortunately, most of the data that has been accumulated related to the cardiovascular issues from RA were collected before the advent of biologic therapy. There is increasing evidence that aggressive management of RA employing the newer biologic agents can help reduce the increased cardiovascular complications related to RA. One example is a study showing that female patients with RA treated with TNF-inhibitors had a reduced overall mortality rate. Unfortunately, the same was not true for men in this one example (Jacobsson LT, Turesson C, Nilsson JA, et al. Ann Rheum Dis. 2007; 66: 670-675).

However other studies have demonstrated a lower rate of cardiovascular problems such as heart attack, stroke, and congestive heart failure) in patients with RA treated with TNF-inhibitors (Dixon WG, Watson KD, Lunt M, et al. Arthritis Rheum. 2007; 56: 2905-2912).

So what should the approach be?

There is still a great deal of ignorance among patients with rheumatoid arthritis regarding the above mentioned complications. Currently, many patients are under the misimpression that natural remedies are good and that drugs are to be avoided, condemned, and are all-in-all, bad. What a mistake!

What rheumatologists must do is explain the reasoning behind the need for aggressive management. It should be explained that there is a narrow “window of opportunity” that makes treatment critical.

Patients should be educated as to the pathophysiology of RA and the terrible consequences that may arise as a result of less than optimal therapy.

While an open mind toward natural therapies is important, an open mind towards the value of proper medical therapies is just as critical.

It is particularly important that patients and physicians become strategic allies together to combat this medical scourge. The aim should be to induce complete remission.

About the Author

Nathan Wei, MD FACP FACR is a nationally known board-certified rheumatologist. For more info:
Arthritis Treatment
and
Tendonitis Treatment Tips

Diabetes, Inflammation, Cancer, Joint, Depression, Relief and Support Part 5


Mortality & Causes of Death in Patients With Rheumatoid Arthritis: A Cross-sectional Population-based Study During the Years 1988-1999 (Acta Universitatis Tamperensis)


Mortality & Causes of Death in Patients With Rheumatoid Arthritis: A Cross-sectional Population-based Study During the Years 1988-1999 (Acta Universitatis Tamperensis)


$72.50



Anti-TNF therapy shown to cut mortality in RA.(Rheumatology)(tumor necrosis factor, rheumatoid arthritis): An article from: Internal Medicine News


Anti-TNF therapy shown to cut mortality in RA.(Rheumatology)(tumor necrosis factor, rheumatoid arthritis): An article from: Internal Medicine News


$9.95


This digital document is an article from Internal Medicine News, published by Thomson Gale on August 1, 2007. The length of the article is 686 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: Anti-T…

TNF inhibitors improve mortality in rheumatoid arthritis.(Musculoskeletal Disorders): An article from: Family Practice News


TNF inhibitors improve mortality in rheumatoid arthritis.(Musculoskeletal Disorders): An article from: Family Practice News


$9.95


This digital document is an article from Family Practice News, published by Thomson Gale on August 1, 2007. The length of the article is 658 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: TNF inhi…

© 2009. All Rights Reserved